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The He Group Publications
2008
50. Yang, C.-G.; Yi, C.; Duguid, E. M.; Sullivan, C. T.; Jian, X.; Rice, P. A.; He, C. "Crystal structures of DNA-RNA repair enzymes AlkB and ABH2 bound to dsDNA" Nature 2008, Accepted.
 
49.  Chang, S.; Bray, S.M.; Li, Z.; Zarnescu, D.C.; He, C.; Jin, P.; Warren, S.T.  "Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila" Nat. Chem. Biol. 2008, Advanced Online Publication. [pdf]
 
48.  Shigdel, U. K.; Zhang, J.; He, C. "Diazirine-Based DNA Photo-Cross-Linking Probes for the Study of Protein-DNA Interactions" Angew. Chem. Intl. Ed. 2008, 47(1), 90-93. [pdf]
 
47.  Chen, C.-S.; Korobkova, E.; Chen, H.; Zhu, J.; Jian, X.; Tao, S.-C.; He, C.; Zhu, H. "A proteome chip approach reveals new DNA damage recognition activities in Escherichia Coli" Nat. Methods, 2008, 5, 69-74. [pdf]
 
2007
46.  Durek, T.; Zhang, J.; He, C.; Kent, S.B.H. "Synthesis of Photoactive Analogues of a Cysteine Knot Trypsin Inhibitor Protein" Org. Lett. 2007, 9 (26), 5497-5500.   [pdf]
 
45. Sarkar, S.K.; Andoy, N.M.; Benitez, J.J.; Chen, P.R.; Kong, J.S.; He, C.; Chen, P. "Engineered Holliday Junctions as Single-Molecule Reporters for Protein-DNA Interactions with Application to a MerR-Family Regulator" J. Am. Chem. Soc. 2007, 129 (41), 12461-12467.  [pdf]
 
44. Chen, P.R.; Wasinger, E. C.; Zhao, J.; van der Lelie, D.; Chen, L.X. ; He, C. "Spectroscopic Insights into Lead(II) Coordination by the Selective Lead(II)-Binding Protein PbrR691" J. Am. Chem. Soc. 2007, 129 (41), 12350-12351. [pdf]
 
43. Li, Z.; Capretto, D.A.; Rahaman, R.O.; He, C. "Gold(III)-Catalyzed Nitrene Insertion into Aromatic and Benzylic C-H Groups" J. Am. Chem. Soc.  2007, 129 (40), 12058-12059. [pdf]
 
42. Brouwer, C.; Rahaman, R O..; He, C. "Gold(I)-Mediated Hydrothiolation of Conjugated Olefins" Synlett 2007, 11, 1785-1789. [pdf] (Invited Contribution)
 
41. Li, Z.; Capretto, D.A.; Rahaman, R.O.; He, C. "Silver-Catalyzed Intermolecular Amination of C-H Groups" Angew. Chem. Intl. Ed. 2007, 46(27), 5184-5186. [pdf] [C&EN]
 
40. Wegner, S. V.; Okesli, A.; Chen, P.; He, C. "Design of an Emission Ratiometric Biosensor from MerR Family Proteins: A Sensitive and Selective Sensor for Hg2+" J. Am. Chem. Soc. 2007, 129(12), 3474-3475. [pdf]
2006
39. Chen, P.; Bae, T.; Williams, W. A.; Duguid, E. M.; Rice, P. A.; Schneewind, O. and He, C. "An Oxidation Sensing Mechanism is Used by A Global Regulator of Staphylococcus aureus" Nature Chem. Biol. 2006, 2, 591-595. [pdf] [C&EN] [IDBD Listing]
 

38.

Li, Z.; Zhang, J.; Brouwer, C.; Yang, C.-G.; Reich, N. W. and He, C. "Bronsted Acid Catalyzed Addition of Phenols, Carboxylic Acids and Tosylamides to Simple Olefin" Org. Lett. 2006, 8(19):4175-8.  [pdf] 

 
37. Li, Z.; Ding, X. and He, C. "Nitrene Transfer Reactions Catalyzed by Gold Complexes" J. Org. Chem. 2006, 71(16):5876-80. [pdf]
 
36. Li, Z. and He, C. "Recent Advances in Silver-Catalyzed Nitrene, Carbene, and Silylene-Transfer Reactions", Euro. J. Org. Chem. 2006, 4313-4322, (an invited review). [pdf]
 
35. 
Mishina, Y. and He, C. "Oxidative Dealkylation DNA Repair Mediated by the Mononuclear Non-Heme
 Iron AlkB Proteins" J. Inorg. Biochem. 2006, 100, 670-678, (an invited review). [pdf] 
 
34. 
Reich, N. W.; Yang, C.-G.; Shi, Z. and He, C. "Gold(I)-Catalyzed Synthesis of Dihydrobenzofurans from
 Aryl Allyl Ethers" Synlett. 2006, 8, 1278-1280, (an invited contribution). [pdf]
 

33.

Brouwer, C. and He, C. “Efficient Gold-Catalyzed Hydroamination of 1,3-Dienes”, Angew Chem. Int. Ed. 2006, 45, 1744-1747. [pdf]

 

32.

Zhang, J.; Yang, C.-G. and He, C. “Gold(I)-Catalyzed Intra- and Intermolecular Hydroamination of Unactivated Olefins ”, J. Am. Chem. Soc. 2006, 128, 1798-1799. [pdf]

 

31.

Mishina, Y.; Duguid, M. E. and He, C. "Direct Reversal of DNA Alkylation Damage", Chem. Rev. 2006, 106, 215-232.  [pdf]

2005

30.

Yang, C.-G.; Reich, N. W. and He, C. “Intramolecular Additions of Alcohols and Carboxylic Acids to Inert Olefins Catalyzed by Silver(I) Triflate”, Org. Lett. 2005, 7, 4553-4556. [pdf]

 

29.

Mishina, Y.; Yang, C.-G. and He, C. “Direct Repair of the Exocyclic DNA Adduct 1,N6-Ethenoadenine by E. coli AlkB and Human ABH3”, J. Am. Chem. Soc. 2005, 127, 14594-14595. [pdf]

 

28.

Li, Z.; Shi, Z. and He, C. "Addition of Heterocycles to Electron Deficient Olefins and Alkynes Catalyzed by Gold(III)", J. Organom. Chem. 2005, 690, 5049-5054 (an invited contribution). [pdf]

 

27.

Yang, C.-G. and He, C. "Gold(I)-Catalyzed Intermolecular Addition of Phenols and Carboxylic Acids to Olefins", J. Am. Chem. Soc. 2005, 127, 6966-6967. [pdf]

 

26.

Duguid, M. E.; Rice, P. A. and He, C. “Implications for How the Human DNA Repair Protein AGT Locates Damage as Revealed from A Unique X-ray Structure of Its DNA Bound Form”, J. Mol. Biol. 2005, 350, 657-666. [pdf]

 

25.

Chen, P.; Greenberg, B.; Taghavi, S.; Romano, C.; van der Lelie, D. and He, C. "An Exceptionally Selective Lead(II)-Regulatory Protein from Ralstonia Metallidurans: Development of A Fluorescent Lead(II) Probe , Angew Chem. Int. Ed 2005, 44, 2715-2719.  [pdf]   C&EN, News1 News2 News3 News4  News5 News6

2004

24.

Mishina, Y.; Chen, L. X. and He, C. “Preparation and Characterization of the Native Iron(II)-Containing AlkB Protein Directly from Escherichia coli”, J. Am. Chem. Soc 2004,  126, 16930-16936. [pdf]

 

23..

Shi, Z. and He, C. “Direct Functionalization of Arenes by Primary Alcohol Sulfonate Esters Catalyzed by Gold(III)”, J. Am. Chem. Soc. 2004, 126, 13596-13597. [pdf]

 

22.

Cui, Y. and He, C. “A Silver-Catalyzed Intramolecular Amidation of Saturated C–H bonds”, Angew Chem. Int. Ed. 2004, 43, 4210-4212. [pdf]

 

21.

Shi, Z. and He, C. “Efficient Functionalization of Aromatic C–H Bonds Catalyzed by Gold(III) under Mild and Solvent Free Conditions”, J. Org. Chem. 2004, 69(11), 3669-3671. [pdf]

 

20.

Shi, Z. and He, C. “An Au-Catalyzed Cyclialkylation of Electron Rich Arenes with Epoxides to Prepare 3-Chromanols”, J. Am. Chem. Soc. 2004, 126, 5964-5965. [pdf]

 

19.

Mishina, Y., Lee, C.-H. J. and He, C. “Potential DNA Preferences of Human and Bacterial AlkB Proteins as Revealed from Chemical Crosslink Studies”, Nucleic Acids Res. 2004, 32, 1548-1554.  [pdf]

 

18.

He, C. and Mishina, Y. “Modeling non-heme iron proteins”, Curr. Opin. Chem. Biol. 2004, 8, 201-208. [pdf]

 

17.

Chen, P. and He, C. “Constructing Highly Sensitive and Selective Fluorescent Biosensors for Metal Ions by Using the MerR Family Proteins”, J. Am. Chem. Soc. 2004, 126, 728-729. [pdf], C&EN  Analytical Chemistry

2003

16.

Cui, Y. and He, C. “Efficient Aziridination of Olefins Catalyzed by A Unique Disilver(I) Compound”, J. Am. Chem. Soc. 2003, 125, 16202-16203. [pdf]

 

15.

Duguid, E. M.; Mishina, Y. and He, C. “A Chemical Disulfide Crosslinking Method to Investigate the Damage-Searching Mechanism of O6-Alkylguanine-DNA Alkyltransferases”, Chem. & Biol. 2003, 10, 827-835. [pdf]

 

14.

Mishina, Y. and He, C. “Probing the Structure and Function of E. coli DNA Alkylation Repair AlkB Protein through Chemical Crosslinking”, J. Am. Chem. Soc.  2003, 125, 8730-8731. [pdf]
Other Publications:

13.  He, C.; Sun, L. J.; Zhou, P.; Norman, D. P. G.; Dötsch, V.; Gross, J. D.; Lane, W. S.; Wagner, G. and Verdine, G. L. “A Zinc-Mediated Electrostatic Switch Controls the Adaptive Response of E. coli to Methylating Agents”, Mol. Cell. 2005, 20, 117-129. [pdf]

12.  He, C.; Wei, H. and Verdine, G. L. “Converting the Sacrificial DNA Repair Protein N-Ada into a Catalytic Methyl Phosphotriester Repair Enzyme”, J. Am. Chem. Soc. 2003, 125, 1450-1451.

11.  He, C. and Verdine, G. L. “Trapping Distinct Structural States of a Protein/DNA Interaction through Disulfide Cross-linking”, Chem. & Biol. 2002, 9, 1297-1303.

10.  He, C.; DuBois, J. L.; Hedman, B.; Hodgson, K. O. and Lippard, S. J. “A short Copper-Copper Distance in a (m-1,2-Peroxo)dicopper(II) Complex Having 1,8-Naphthyridine Unit as an Additional Bridge”, Angew. Chem. Int. Ed. Engl. 2001, 40, 1484-1487.

9.  He, C. and Lippard, S. J. “Synthesis and Electrochemical Studies of Diiron Complexes of 1,8-Naphthyridine-Based Dinucleating Ligands to Model Features of the Active Sites of Non-Heme Diiron Enzymes”, Inorg. Chem. 2001, 40, 1414-1420 (cover story).

8.  He, C.; Barrios, A. M.; Lee, D.; Kuzelka, J.; Davydov, R. M. and Lippard, S. J. “Diiron Complexes of 1,8-Naphthyridine-Based Dinucleating Ligands as Models for Hemerythrin”, J. Am. Chem. Soc. 2000, 122, 12683-12690.

7.   He, C. and Lippard, S. J. “Synthesis and Characterization of Several Dicopper(I) Complexes and a Spin-Delocalized Dicopper(I,II) Mixed-Valence Complex Using a 1,8-Naphthyridine-Based Dinucleating Ligand”, Inorg. Chem. 2000, 39, 5225-5231.

6.  He, C. and Lippard, S. J. “Design and Synthesis of Multidentate Dinucleating Ligands Based on 1,8-Naphthyridine”, Tetrahedron 2000, 56, 8245-8252.

5.  He, C.; Gomez, V.; Spingler, B. and Lippard, S. J. “Monodentate-Bridged Phosphodiester and Sulfate Complexes: Structural Insight into the Biological Activation of Phosphodiesters, Sulfate, and Sulfate Esters”, Inorg. Chem. 2000, 39, 4188-4189.

4.  Kaminskaia, N. V.; He, C. and Lippard, S. J. “Reactivity of m-Hydroxodizinc(II) Centers in Enzymatic Catalysis through Model Studies”, Inorg. Chem. 2000, 39, 3365-3373.

3.  He, C. and Lippard, S. J. “Modeling Carboxylate-Bridged Dinuclear Active Sites in Metalloenzymes Using a Novel Naphthyridine-Based Dinucleating Ligand”, J. Am. Chem. Soc. 2000, 122, 184-185.

2.  He, C. and Lippard, S. J. “Aminoguanidinium Hydrolysis Effected by a Hydroxo-Bridged Dicobalt(II) Complexes”, J. Am. Chem. Soc. 1998, 120, 105-113.

1.  Qian, Y.; Xie, Y.; He, C.; Li, J. and Chen, Z. “Hydrothermal Preparation and Characterization of Ultrafine Magnetite Powders”, Material Research Bulletin 1994, 29, 953-957.